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Total cholesterol levels

near ERGIC3 · rs6119625

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs6119625 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs6119625 rs6119625 near ERGIC3

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0414 lower (95% confidence interval 0.029-0.054); p = 9 × 10−11.

How common The G allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 20, band 20q11.22 — in an intron of FER1L4.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Total cholesterol levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total cholesterol levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total cholesterol levels compared to the general population.
Source

Questions about rs6119625

What is rs6119625?

rs6119625 is a single position in the genome, in or near the near ERGIC3 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6119625 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs6119625 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6119625 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total cholesterol levels (rs6119625). MyGeneLog™. https://www.mygenelog.com/variants/rs6119625

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