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Who was studied 12,024 Chinese ancestry cases, 67,845 Chinese ancestry controls; replicated in 3,369 East Asian ancestry cases, 14,325 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.353 higher (95% confidence interval 0.28-0.43); p = 3 × 10−21.
Where it sits Chromosome 7, band 7q32.1 — between genes, 0.7 kb from PAX4.
What each result means
C/CNo copy of the version the research linked to Gestational diabetes mellitus. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Gestational diabetes mellitus. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Gestational diabetes mellitus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40325049 · open access
Questions about rs61160304
What is rs61160304?
rs61160304 is a single position in the genome, in or near the near PAX4 gene. Published research associates it with gestational diabetes mellitus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs61160304 linked to?
On MyGeneLog this position is linked to Gestational Diabetes Mellitus. The research behind each link, and its sources, are set out on that condition page.
Does having rs61160304 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs61160304 come from?
GWAS Catalog, Nature communications 2025, PMID:40325049. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 251222117Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others17Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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