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Terminally Differentiated CD4-CD8- T cell Absolute Count

near HLA-DQA1 · rs61126090

What the study found

Who was studied 3,395 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.267 lower (95% confidence interval 0.19-0.34); p = 1 × 10−12.

How common The G allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 9.6 kb from HLA-DQA1.

What each result means

A/A No copy of the version the research linked to Terminally Differentiated CD4-CD8- T cell Absolute Count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Terminally Differentiated CD4-CD8- T cell Absolute Count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Terminally Differentiated CD4-CD8- T cell Absolute Count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61126090

What is rs61126090?

rs61126090 is a single position in the genome, in or near the near HLA-DQA1 gene. Published research associates it with terminally differentiated cd4-cd8- t cell absolute count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61126090 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61126090 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Terminally Differentiated CD4-CD8- T cell Absolute Count (rs61126090). MyGeneLog™. https://www.mygenelog.com/variants/rs61126090

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