A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diastolic blood pressure compared to the general population.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diastolic blood pressure.
C/CPublished research associates this genotype with typical/baseline likelihood of Diastolic blood pressure — no copies of the reported risk allele.
Nature genetics · 2017 · PMID 28135244 · open access
Questions about rs6108168
What is rs6108168?
rs6108168 is a single position in the genome, in or near the PLCB1 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6108168 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs6108168 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6108168 come from?
GWAS Catalog, Nat Genet 2017, PMID:28135244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.