Standard

Daytime sleepiness

near LBP · rs6099524

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 112,717 European ancestry cases and controls.

The effect Each copy of the T allele shifted the measure 0.29 higher (95% confidence interval 0.2-0.38); p = 1 × 10⁻⁹.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 20, band 20q11.23 — between genes, 2.8 kb from LOC124904901.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Daytime sleepiness — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Daytime sleepiness.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Daytime sleepiness compared to the general population.

Source

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

Hammerschlag AR, Stringer S, de Leeuw CA, Sniekers S, Taskesen E, Watanabe K, Blanken TF, Dekker K, Te Lindert BHW, Wassing R, Jonsdottir I, Thorleifsson G

and 10 more — show all

Stefansson H, Gislason T, Berger K, Schormair B, Wellmann J, Winkelmann J, Stefansson K, Oexle K, Van Someren EJW, Posthuma D

Nature genetics · 2017 · PMID 28604731 · open access

Questions about rs6099524

What is rs6099524?

rs6099524 is a single position in the genome, in or near the near LBP gene. Published research associates it with daytime sleepiness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6099524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6099524 come from?

GWAS Catalog, Nat Genet 2017, PMID:28604731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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