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Platelet-to-lymphocyte ratio

MIR4435-2HG · rs60756694

What the study found

Who was studied 234,552 European ancestry individuals; replicated in 100,478 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−13.

How common The A allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 2, band 2q13 — in an intron of MIR4435-2HG.

What each result means

A/A Two copies of the version the research linked to Platelet-to-lymphocyte ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet-to-lymphocyte ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet-to-lymphocyte ratio. This is the starting point the study compared everyone against.
Source

Questions about rs60756694

What is rs60756694?

rs60756694 is a single position in the genome, in or near the MIR4435-2HG gene. Published research associates it with platelet-to-lymphocyte ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs60756694 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs60756694 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet-to-lymphocyte ratio (rs60756694). MyGeneLog™. https://www.mygenelog.com/variants/rs60756694

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