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Odorant perception

OR6C70 · rs60683621

What the study found

Who was studied 9,122 Icelandic ancestry individuals; replicated in 2,204 Icelandic ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.13 higher (95% confidence interval 0.10-0.16); p = 9 × 10−16.

How common The G allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 12, band 12q13.2 — a missense change in OR6C70.

What each result means

C/C No copy of the version the research linked to Odorant perception. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Odorant perception. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Odorant perception. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs60683621

What is rs60683621?

rs60683621 is a single position in the genome, in or near the OR6C70 gene. Published research associates it with odorant perception. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs60683621 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs60683621 come from?

GWAS Catalog, Current biology : CB 2020, PMID:33035477. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Odorant perception (rs60683621). MyGeneLog™. https://www.mygenelog.com/variants/rs60683621

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