C/CPublished research associates this genotype with typical/baseline likelihood of Cotinine glucuronidation — no copies of the reported risk allele. (GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2014, PMID:25293881)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cotinine glucuronidation. (GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2014, PMID:25293881)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cotinine glucuronidation compared to the general population. (GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2014, PMID:25293881)
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015 · PMID 25293881
Questions about rs60634637
What is rs60634637?
rs60634637 is a single position in the genome, in or near the KLF4 gene. Published research associates it with cotinine glucuronidation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs60634637 linked to?
On MyGeneLog this position is linked to Nicotine and Cotinine Metabolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs60634637 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs60634637 come from?
GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2014, PMID:25293881. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.