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Lung function (FVC)

near LINC00489 · rs6063386

What the study found

Who was studied 100,285 Chinese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.03 L higher; p = 5 × 10−10.

How common The C allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 20, band 20q11.23 — between genes, 5.6 kb from LINC00489.

What each result means

C/C Two copies of the version the research linked to Lung function (FVC). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lung function (FVC). That is a smaller link than two copies.
T/T No copy of the version the research linked to Lung function (FVC). This is the starting point the study compared everyone against.
Source

Questions about rs6063386

What is rs6063386?

rs6063386 is a single position in the genome, in or near the near LINC00489 gene. Published research associates it with lung function (fvc). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6063386 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6063386 come from?

GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lung function (FVC) (rs6063386). MyGeneLog™. https://www.mygenelog.com/variants/rs6063386

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