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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,959 European ancestry cases who discontinued ACEi, 44,041 European ancestry controls who continued ACEi treatment.
The effect
Each copy of the T allele carried 1.21 times the odds of ACE-inhibitor discontinuation (95% confidence interval 1.17-1.24); p = 2 × 10−34.
How common The T allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 20, band 20q13.33 — between genes, 4.1 kb from LINC00686.
What each result means
C/CNo copy of the version the research linked to ACE-inhibitor discontinuation. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to ACE-inhibitor discontinuation. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to ACE-inhibitor discontinuation. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6062847 is a single position in the genome, in or near the near LINC00686 gene. Published research associates it with ace-inhibitor discontinuation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6062847 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6062847 come from?
GWAS Catalog, European heart journal 2022, PMID:35751511. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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