Sensitive

Colorectal cancer

RPS21 · rs6061231

Where this position leads

Condition: Colorectal Cancer

rs6061231 Condition: Colorectal Cancer Colorectal Cancer Condition rs6061231 rs6061231 RPS21

What the study found

Who was studied 4,508 East Asian ancestry cases, 16,588 East Asian ancestry controls; replicated in 11,044 East Asian ancestry cases, 18,036 East Asian ancestry controls.

The effect Each copy of the C allele carried 1.18 times the odds of Colorectal cancer (95% confidence interval 1.13-1.25); p = 8 × 10−11.

How common The C allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 20, band 20q13.33 — between genes, 3 kb from LOC105372708.

What each result means

A/A No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6061231

What is rs6061231?

rs6061231 is a single position in the genome, in or near the RPS21 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6061231 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs6061231 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6061231 come from?

GWAS Catalog, Gastroenterology 2016, PMID:26965516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs6061231). MyGeneLog™. https://www.mygenelog.com/variants/rs6061231

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