Standard

Height

FAM83C · rs6060347

Where this position leads

Condition: Height

rs6060347 Condition: Height Height Condition rs6060347 rs6060347 FAM83C

What the study found

Who was studied 1,249 whole genome sequenced European ancestry individuals, 3,541 whole genome sequenced individuals, 46,910 European ancestry individuals, 471 Carlantino (founder/genetic isolate) individuals, 1,197 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,043 Mylopotamos (founder/genetic isolate) individuals, 933 Pomak (founder/genetic isolate) individuals, 1,785 Val Borbera (founder/genetic isolate) individuals; replicated in 205,003 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0521 lower (95% confidence interval 0.037-0.067); p = 2 × 10−11.

How common The A allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 20, band 20q11.22 — in the 3′ untranslated region of FAM83C.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs6060347

What is rs6060347?

rs6060347 is a single position in the genome, in or near the FAM83C gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6060347 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs6060347 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6060347 come from?

GWAS Catalog, Am J Hum Genet 2017, PMID:28552196. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Height (rs6060347). MyGeneLog™. https://www.mygenelog.com/variants/rs6060347

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