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Who was studied 38,000 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.754 lower (95% confidence interval 0.69-0.82); p = 1 × 10−103.
Where it sits Chromosome 11, band 11p15.4 — in an intron of HBE1.
What each result means
A/ANo copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39414775 · open access
Questions about rs60586182
What is rs60586182?
rs60586182 is a single position in the genome, in or near the HBE1 gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs60586182 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs60586182 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs60586182 come from?
GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 132227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Mean corpuscular hemoglobin (rs60586182). MyGeneLog™. https://www.mygenelog.com/variants/rs60586182