Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications
HLA-F-AS1 · rs60581484
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 133 Japanese ancestry cases, 418 Japanese ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−13.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — in the 3′ untranslated region of HLA-F-AS1.
What each result means
A/ATwo copies of the version the research linked to Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications. This is the starting point the study compared everyone against.
NPJ genomic medicine · 2021 · PMID 33574277 · open access
Questions about rs60581484
What is rs60581484?
rs60581484 is a single position in the genome, in or near the HLA-F-AS1 gene. Published research associates it with cold medicine-related stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) with severe ocular complications. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs60581484 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs60581484 come from?
GWAS Catalog, NPJ genomic medicine 2021, PMID:33574277. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications (rs60581484). MyGeneLog™. https://www.mygenelog.com/variants/rs60581484