0 333219223110Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 120,246 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.123 lower; p = 2 × 10−53.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 4, band 4q31.3 — a missense change in FGB.
What ClinVar records
ClassificationConflicting classifications of pathogenicity for Congenital afibrinogenemia, Abnormal bleeding, Hypofibrinogenemia, Thrombocytopenia, Afibrinogenemia and 3 more; criteria provided, conflicting classifications (1 of 4 stars, 13 submitters), last evaluated 2026-01-19.
ClinVar record 517313NM_005141.5(FGB):c.794C>T (p.Pro265Leu)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Fibrinogen levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Fibrinogen levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Fibrinogen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6054 is a single position in the genome, in or near the FGB gene. Published research associates it with fibrinogen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6054 linked to?
On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.
Does having rs6054 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6054 come from?
GWAS Catalog, Hum Mol Genet 2015, PMID:26561523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 333219223110Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.