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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,127 African American or Afro-Caribbean cases, 101,748 African American or Afro-Caribbean controls, 3,724 Hispanic or Latin American cases, 54,427 Hispanic or Latin American controls, 360 East Asian ancestry cases, 6,302 East Asian ancestry controls, 34,069 European ancestry cases, 399,129 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.166 lower (95% confidence interval 0.14-0.19); p = 8 × 10−26.
How common The G allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 22, band 22q12.3 — between genes, 3.6 kb from APOL1.
What each result means
A/ANo copy of the version the research linked to Hypertensive chronic kidney disease (PheCode 401.22). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hypertensive chronic kidney disease (PheCode 401.22). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hypertensive chronic kidney disease (PheCode 401.22). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs60295735
What is rs60295735?
rs60295735 is a single position in the genome, in or near the near APOL1 gene. Published research associates it with hypertensive chronic kidney disease (phecode 401.22). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs60295735 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs60295735 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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