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Thigh subcutaneous adipose tissue volume

near MAFB · rs6029180

What the study found

Who was studied 37,589 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.04 higher (95% confidence interval 0.02-0.06); p = 2 × 10−11.

How common The G allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 20, band 20q12 — between genes, 135.6 kb from MAFB.

What each result means

A/A No copy of the version the research linked to Thigh subcutaneous adipose tissue volume. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Thigh subcutaneous adipose tissue volume. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Thigh subcutaneous adipose tissue volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6029180

What is rs6029180?

rs6029180 is a single position in the genome, in or near the near MAFB gene. Published research associates it with thigh subcutaneous adipose tissue volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6029180 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6029180 come from?

GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thigh subcutaneous adipose tissue volume (rs6029180). MyGeneLog™. https://www.mygenelog.com/variants/rs6029180

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