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Mean platelet volume in pregnancy

PRC1-AS1 · rs60290423

What the study found

Who was studied 96,062 Chinese ancestry individuals; replicated in 46,276 Chinese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0448 higher (95% confidence interval 0.03-0.059); p = 1 × 10−9.

How common The C allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 15, band 15q26.1 — in an intron of PRC1-AS1.

What each result means

C/C Two copies of the version the research linked to Mean platelet volume in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet volume in pregnancy. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet volume in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs60290423

What is rs60290423?

rs60290423 is a single position in the genome, in or near the PRC1-AS1 gene. Published research associates it with mean platelet volume in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs60290423 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs60290423 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean platelet volume in pregnancy (rs60290423). MyGeneLog™. https://www.mygenelog.com/variants/rs60290423

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