Standard
Asparaginase hypersensitivity in acute lymphoblastic leukemia
NFATC2 · rs6021191
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Asparaginase hypersensitivity in acute lymphoblastic leukemia — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Asparaginase hypersensitivity in acute lymphoblastic leukemia.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Asparaginase hypersensitivity in acute lymphoblastic leukemia compared to the general population.
Source
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity
Fernandez CA,
Smith C,
Yang W,
Mullighan CG,
Qu C,
Larsen E,
Bowman WP,
Liu C,
Ramsey LB,
Chang T,
Karol SE,
Loh ML
and 9 more — show all
Blood · 2015 · PMID 25987655
Questions about rs6021191
What is rs6021191?
rs6021191 is a single position in the genome, in or near the NFATC2 gene. Published research associates it with asparaginase hypersensitivity in acute lymphoblastic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6021191 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6021191 come from?
GWAS Catalog, Blood 2015, PMID:25987655. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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