0 131237Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 38,518 African American or Afro-Caribbean cases, 16,987 African American or Afro-Caribbean controls, 16,330 Hispanic or Latin American cases, 12,984 Hispanic or Latin American controls, 2,059 East Asian ancestry cases, 1,488 East Asian ancestry controls, 191,352 European ancestry cases, 124,316 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.058 lower (95% confidence interval 0.044-0.072); p = 1 × 10−13.
How common The C allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 20, band 20q13.12 — in a non-coding transcript of JPH2.
What ClinVar records
ClassificationBenign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2025-04-09.
ClinVar record 3894891NM_020433.5(JPH2):c.379+4772G>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CTwo copies of the version the research linked to High blood pressure / hypertension. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to High blood pressure / hypertension. That is a smaller link than two copies.
G/GNo copy of the version the research linked to High blood pressure / hypertension. This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs6017285
What is rs6017285?
rs6017285 is a single position in the genome, in or near the JPH2 gene. Published research associates it with high blood pressure / hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6017285 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs6017285 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6017285 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 131237Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
High blood pressure / hypertension (rs6017285). MyGeneLog™. https://www.mygenelog.com/variants/rs6017285