Standard
Fibrinogen
SHANK3 · rs6010044
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fibrinogen compared to the general population. (GWAS Catalog, Circulation 2013, PMID:23969696)
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fibrinogen. (GWAS Catalog, Circulation 2013, PMID:23969696)
C/C
Published research associates this genotype with typical/baseline likelihood of Fibrinogen — no copies of the reported risk allele. (GWAS Catalog, Circulation 2013, PMID:23969696)
Source
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease
Sabater-Lleal M,
Huang J,
Chasman D,
Naitza S,
Dehghan A,
Johnson AD,
Teumer A,
Reiner AP,
Folkersen L,
Basu S,
Rudnicka AR,
Trompet S
and 133 more — show all
Mälarstig A,
Baumert J,
Bis JC,
Guo X,
Hottenga JJ,
Shin SY,
Lopez LM,
Lahti J,
Tanaka T,
Yanek LR,
Oudot-Mellakh T,
Wilson JF,
Navarro P,
Huffman JE,
Zemunik T,
Redline S,
Mehra R,
Pulanic D,
Rudan I,
Wright AF,
Kolcic I,
Polasek O,
Wild SH,
Campbell H,
Curb JD,
Wallace R,
Liu S,
Eaton CB,
Becker DM,
Becker LC,
Bandinelli S,
Räikkönen K,
Widen E,
Palotie A,
Fornage M,
Green D,
Gross M,
Davies G,
Harris SE,
Liewald DC,
Starr JM,
Williams FM,
Grant PJ,
Spector TD,
Strawbridge RJ,
Silveira A,
Sennblad B,
Rivadeneira F,
Uitterlinden AG,
Franco OH,
Hofman A,
van Dongen J,
Willemsen G,
Boomsma DI,
Yao J,
Swords Jenny N,
Haritunians T,
McKnight B,
Lumley T,
Taylor KD,
Rotter JI,
Psaty BM,
Peters A,
Gieger C,
Illig T,
Grotevendt A,
Homuth G,
Völzke H,
Kocher T,
Goel A,
Franzosi MG,
Seedorf U,
Clarke R,
Steri M,
Tarasov KV,
Sanna S,
Schlessinger D,
Stott DJ,
Sattar N,
Buckley BM,
Rumley A,
Lowe GD,
McArdle WL,
Chen MH,
Tofler GH,
Song J,
Boerwinkle E,
Folsom AR,
Rose LM,
Franco-Cereceda A,
Teichert M,
Ikram MA,
Mosley TH,
Bevan S,
Dichgans M,
Rothwell PM,
Sudlow CL,
Hopewell JC,
Chambers JC,
Saleheen D,
Kooner JS,
Danesh J,
Nelson CP,
Erdmann J,
Reilly MP,
Kathiresan S,
Schunkert H,
Morange PE,
Ferrucci L,
Eriksson JG,
Jacobs D,
Deary IJ,
Soranzo N,
Witteman JC,
de Geus EJ,
Tracy RP,
Hayward C,
Koenig W,
Cucca F,
Jukema JW,
Eriksson P,
Seshadri S,
Markus HS,
Watkins H,
Samani NJ,
Wallaschofski H,
Smith NL,
Tregouet D,
Ridker PM,
Tang W,
Strachan DP,
Hamsten A,
O'Donnell CJ
Circulation · 2013 · PMID 23969696
Questions about rs6010044
What is rs6010044?
rs6010044 is a single position in the genome, in or near the SHANK3 gene. Published research associates it with fibrinogen. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6010044 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6010044 come from?
GWAS Catalog, Circulation 2013, PMID:23969696. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants