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Who was studied 7,045 European ancestry cases, 449,282 European ancestry controls.
The effect
Each copy of the T allele carried 1.11 times the odds of Inflammatory bowel disease; p = 1 × 10−9.
How common The T allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 21, band 21q22.3 — inside GATD3.
What each result means
C/CNo copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2021 · PMID 33608531 · open access
Questions about rs59998884
What is rs59998884?
rs59998884 is a single position in the genome, in or near the GATD3 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs59998884 linked to?
On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs59998884 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs59998884 come from?
GWAS Catalog, Nature communications 2021, PMID:33608531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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