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Who was studied 49,905 European ancestry cases, 752,392 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0787 lower (95% confidence interval 0.063-0.094); p = 7 × 10−23.
Where it sits Chromosome 12, band 12q13.13 — between genes, 8.3 kb from KRT6A.
What each result means
A/ANo copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2024 · PMID 38182794 · open access
Questions about rs599466
What is rs599466?
rs599466 is a single position in the genome, in or near the near KRT6A gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs599466 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs599466 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs599466 come from?
GWAS Catalog, Communications biology 2024, PMID:38182794. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8215Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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