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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 28,204 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.067 lower (95% confidence interval 0.045-0.089); p = 2 × 10−10.
How common The G allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 22, band 22q11.21 — in an intron of MICAL3.
What each result means
G/GTwo copies of the version the research linked to ACE2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to ACE2 levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to ACE2 levels. This is the starting point the study compared everyone against.
rs5992134 is a single position in the genome, in or near the MICAL3 gene. Published research associates it with ace2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs5992134 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5992134 come from?
GWAS Catalog, Circulation 2022, PMID:35387486. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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