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SUMF2 protein levels

near VOPP1-DT · rs59870551

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0551 lower (95% confidence interval 0.043-0.068); p = 3 × 10−20.

How common The A allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 7, band 7p11.2 — between genes, 3.2 kb from VOPP1-DT.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of SUMF2 protein levels compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with SUMF2 protein levels.
C/C Published research associates this genotype with typical/baseline likelihood of SUMF2 protein levels — no copies of the reported risk allele.
Source

Questions about rs59870551

What is rs59870551?

rs59870551 is a single position in the genome, in or near the near VOPP1-DT gene. Published research associates it with sumf2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs59870551 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs59870551 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

SUMF2 protein levels (rs59870551). MyGeneLog™. https://www.mygenelog.com/variants/rs59870551

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