G/GPublished research associates this genotype with typical/baseline likelihood of Rheumatoid arthritis — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Rheumatoid arthritis.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Rheumatoid arthritis compared to the general population.
rs59716545 is a single position in the genome, in or near the IKZF3 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs59716545 linked to?
On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs59716545 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs59716545 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:30423114. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.