SRGN protein level (protein group normalized intensity)
CPAMD8 · rs59665139
0 1522326Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,256 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.203 lower (95% confidence interval 0.13-0.27); p = 9 × 10−9.
How common The A allele had a frequency of about 42% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in an intron of CPAMD8.
What each result means
A/ATwo copies of the version the research linked to SRGN protein level (protein group normalized intensity). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to SRGN protein level (protein group normalized intensity). That is a smaller link than two copies.
G/GNo copy of the version the research linked to SRGN protein level (protein group normalized intensity). This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 41310232 · open access
Questions about rs59665139
What is rs59665139?
rs59665139 is a single position in the genome, in or near the CPAMD8 gene. Published research associates it with srgn protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs59665139 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs59665139 come from?
GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1522326Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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SRGN protein level (protein group normalized intensity) (rs59665139). MyGeneLog™. https://www.mygenelog.com/variants/rs59665139