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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 91,105 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.028 SD units lower (95% confidence interval 0.018-0.038); p = 2 × 10−9.
How common The A allele had a frequency of about 66% in the people studied.
Where it sits Chromosome 18, band 18q12.3 — between genes, 72.6 kb from RIT2.
What each result means
A/ATwo copies of the version the research linked to Physical activity (overall physical activity time). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Physical activity (overall physical activity time). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Physical activity (overall physical activity time). This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30531941 · open access
Questions about rs59499656
What is rs59499656?
rs59499656 is a single position in the genome, in or near the SYT4 gene. Published research associates it with physical activity (overall physical activity time). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs59499656 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs59499656 come from?
GWAS Catalog, Nat Commun 2018, PMID:30531941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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