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Who was studied 1,854 European ancestry cases, 21,372 European ancestry controls; replicated in 8,239 European ancestry cases, 7,590 European ancestry controls.
The effect
Each copy of the A allele carried 1.23 times the odds of Prostate cancer (95% confidence interval 1.16-1.30); p = 4 × 10−13.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome X, band Xp11.22 — between genes, 3.2 kb from NUDT11.
What each result means
A/ATwo copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
rs5945572 is a single position in the genome, in or near the LOC340602 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs5945572 linked to?
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs5945572 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5945572 come from?
GWAS Catalog, Nature genetics 2008, PMID:18264098. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 101423Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot4Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Prostate cancer (rs5945572). MyGeneLog™. https://www.mygenelog.com/variants/rs5945572