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Systolic blood pressure

near NHLRC2 · rs59448728

Where this position leads

Condition: Blood Pressure

rs59448728 Condition: Blood Pressure Blood Pressure Condition rs59448728 rs59448728 near NHLRC2

What the study found

Who was studied 145,505 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0239 higher (95% confidence interval 0.016-0.032); p = 1 × 10−8.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 10, band 10q25.3 — between genes, 33.7 kb from NHLRC2.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs59448728

What is rs59448728?

rs59448728 is a single position in the genome, in or near the near NHLRC2 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs59448728 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs59448728 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs59448728 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs59448728). MyGeneLog™. https://www.mygenelog.com/variants/rs59448728

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