Standard

Triglycerides

near CRIPTO3 · rs5942951

Where this position leads

Condition: High Triglycerides

rs5942951 Condition: High Triglycerides High Triglycerides Condition rs5942951 rs5942951 near CRIPTO3

What the study found

Who was studied 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0244 lower (95% confidence interval 0.021-0.028); p = 2 × 10−36.

Where it sits Chromosome X, band Xq23 — between genes, 5.6 kb from CRIPTO3.

What each result means

A/A Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

Questions about rs5942951

What is rs5942951?

rs5942951 is a single position in the genome, in or near the near CRIPTO3 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs5942951 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs5942951 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5942951 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs5942951). MyGeneLog™. https://www.mygenelog.com/variants/rs5942951

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