ST3GAL4 · rs59379014
Where this position leads
Condition: Cholesterol (LDL, HDL and Total)
What the study found
Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.067 lower; p = 6 × 10−14.
Where it sits Chromosome 11, band 11q24.2 — in an intron of ST3GAL4.
rs59379014 is a single position in the genome, in or near the ST3GAL4 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Total cholesterol levels (rs59379014). MyGeneLog™. https://www.mygenelog.com/variants/rs59379014