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Cortical surface area

near LINC01364 · rs59373415

What the study found

Who was studied 33,992 European ancestry individuals; replicated in 14,727 European ancestry individuals, 2,943 individuals.

The effect Each copy of the C allele shifted the measure 19.9 higher (95% confidence interval 14.07-25.71); p = 2 × 10−11.

How common The C allele had a frequency of about 83% in the people studied.

Where it sits Chromosome 1, band 1p22.3 — between genes, 36.3 kb from LINC01364.

What each result means

C/C Two copies of the version the research linked to Cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs59373415

What is rs59373415?

rs59373415 is a single position in the genome, in or near the near LINC01364 gene. Published research associates it with cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs59373415 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs59373415 come from?

GWAS Catalog, Science (New York, N.Y.) 2020, PMID:32193296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical surface area (rs59373415). MyGeneLog™. https://www.mygenelog.com/variants/rs59373415

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