Standard

White matter microstructure (fractional anisotropy) Fornix (PC1)

GPM6B · rs5934135

What the study found

Who was studied 37,772 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 7.27 z score lower; p = 4 × 10−13.

Where it sits Chromosome X, band Xp22.2 — in an intron of GPM6B.

What each result means

C/C Two copies of the version the research linked to White matter microstructure (fractional anisotropy) Fornix (PC1). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to White matter microstructure (fractional anisotropy) Fornix (PC1). That is a smaller link than two copies.
G/G No copy of the version the research linked to White matter microstructure (fractional anisotropy) Fornix (PC1). This is the starting point the study compared everyone against.
Source

Questions about rs5934135

What is rs5934135?

rs5934135 is a single position in the genome, in or near the GPM6B gene. Published research associates it with white matter microstructure (fractional anisotropy) fornix (pc1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs5934135 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5934135 come from?

GWAS Catalog, Science advances 2025, PMID:39854466. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White matter microstructure (fractional anisotropy) Fornix (PC1) (rs5934135). MyGeneLog™. https://www.mygenelog.com/variants/rs5934135

← See all variants