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Insomnia

CYCL1 · rs5922858

Where this position leads

Condition: Insomnia

rs5922858 Condition: Insomnia Insomnia Condition rs5922858 rs5922858 CYCL1

What the study found

Who was studied up to 12,674 European ancestry male cases, up to 19,481 European ancestry female cases, up to 16,009 European ancestry male controls, up to 10,964 European ancestry female controls,.

The effect Each copy of the G allele carried 1.12 times the odds of Insomnia (95% confidence interval 1.07–1.16); p = 1 × 10−8.

Where it sits Chromosome X, band Xq21.1 — between genes, 32.6 kb from TERF1P4.

What each result means

G/G Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
Source

Questions about rs5922858

What is rs5922858?

rs5922858 is a single position in the genome, in or near the CYCL1 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs5922858 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs5922858 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5922858 come from?

GWAS Catalog, Nat Genet 2016, PMID:27992416. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs5922858). MyGeneLog™. https://www.mygenelog.com/variants/rs5922858

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