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Who was studied 31,904 European ancestry cases, 172,474 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0831 lower (95% confidence interval 0.054-0.113); p = 4 × 10−8.
How common The G allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 1, band 1p36.11 — between genes, 11.9 kb from AHDC1.
What each result means
A/ANo copy of the version the research linked to Medication use (calcium channel blockers). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Medication use (calcium channel blockers). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Medication use (calcium channel blockers). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31015401 · open access
Questions about rs59180873
What is rs59180873?
rs59180873 is a single position in the genome, in or near the RP1-159A19.4 gene. Published research associates it with medication use (calcium channel blockers). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs59180873 linked to?
On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.
Does having rs59180873 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs59180873 come from?
GWAS Catalog, Nature communications 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Medication use (calcium channel blockers) (rs59180873). MyGeneLog™. https://www.mygenelog.com/variants/rs59180873