Standard

Intraocular pressure

GLCCI1 · rs59072263

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Intraocular pressure compared to the general population. (GWAS Catalog, Hum Mol Genet 2013, PMID:23836780)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Intraocular pressure. (GWAS Catalog, Hum Mol Genet 2013, PMID:23836780)

T/T Published research associates this genotype with typical/baseline likelihood of Intraocular pressure — no copies of the reported risk allele. (GWAS Catalog, Hum Mol Genet 2013, PMID:23836780)

Source

Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus

Blue Mountains Eye Study (BMES) · Wellcome Trust Case Control Consortium 2 (WTCCC2)

Human molecular genetics · 2013 · PMID 23836780 · open access

Questions about rs59072263

What is rs59072263?

rs59072263 is a single position in the genome, in or near the GLCCI1 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs59072263 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs59072263 come from?

GWAS Catalog, Hum Mol Genet 2013, PMID:23836780. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants