Standard

Stable warfarin dose

near CYP2C9 · rs58800757

What the study found

Who was studied 762 Black African ancestry individuals, 133 Mixed ancestry individuals, 94 Black African or Mixed ancestry individuals, 515 African American individuals.

The effect Each copy of the G allele shifted the measure 0.277 lower (95% confidence interval 0.2-0.35); p = 4 × 10−13.

How common The G allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 10, band 10q23.33 — between genes, 8.4 kb from CYP2C9.

What each result means

A/A No copy of the version the research linked to Stable warfarin dose. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Stable warfarin dose. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Stable warfarin dose. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs58800757

What is rs58800757?

rs58800757 is a single position in the genome, in or near the near CYP2C9 gene. Published research associates it with stable warfarin dose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs58800757 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs58800757 come from?

GWAS Catalog, Blood advances 2024, PMID:39163621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Stable warfarin dose (rs58800757). MyGeneLog™. https://www.mygenelog.com/variants/rs58800757

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