Standard

Diastolic blood pressure

MAPK4 · rs58693787

Where this position leads

Condition: Blood Pressure

rs58693787 Condition: Blood Pressure Blood Pressure Condition rs58693787 rs58693787 MAPK4

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.168 higher (95% confidence interval 0.12-0.21); p = 3 × 10−12.

Where it sits Chromosome 18, band 18q21.1 — in an intron of MAPK4.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs58693787

What is rs58693787?

rs58693787 is a single position in the genome, in or near the MAPK4 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs58693787 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs58693787 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs58693787 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs58693787). MyGeneLog™. https://www.mygenelog.com/variants/rs58693787

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