0 22171238Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls; replicated in 57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls.
The effect
Each copy of the C allele carried 1.07 times the odds of Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) (95% confidence interval 1.04-1.09); p = 3 × 10−8.
How common The C allele had a frequency of about 84% in the people studied.
Where it sits Chromosome 2, band 2p24.1 — between genes, 3.6 kb from APOB.
What each result means
A/ANo copy of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs585967 is a single position in the genome, in or near the APOB gene. Published research associates it with coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs585967 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs585967 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs585967 come from?
GWAS Catalog, Nat Genet 2017, PMID:28714975. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22171238Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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