Standard

Body mass index

PMS2P3 · rs58513914

Where this position leads

Condition: Childhood Body Mass Index

rs58513914 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs58513914 rs58513914 PMS2P3

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0185 lower (95% confidence interval 0.013-0.024); p = 2 × 10−12.

Where it sits Chromosome 7, band 7q11.23 — in an intron of PMS2P3.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs58513914

What is rs58513914?

rs58513914 is a single position in the genome, in or near the PMS2P3 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs58513914 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs58513914 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs58513914 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs58513914). MyGeneLog™. https://www.mygenelog.com/variants/rs58513914

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