ICD10 N92: Excessive, frequent and irregular menstruation
SYNE1 · rs584336
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 60,359 European ancestry cases, 189,515 European ancestry controls.
The effect
Each copy of the G allele carried 0.95 times the odds of ICD10 N92: Excessive, frequent and irregular menstruation (95% confidence interval 0.94-0.97); p = 4 × 10−10.
Where it sits Chromosome 6, band 6q25.2 — in an intron of SYNE1.
What each result means
A/ANo copy of the version the research linked to ICD10 N92: Excessive, frequent and irregular menstruation. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to ICD10 N92: Excessive, frequent and irregular menstruation. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to ICD10 N92: Excessive, frequent and irregular menstruation. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs584336 is a single position in the genome, in or near the SYNE1 gene. Published research associates it with icd10 n92: excessive, frequent and irregular menstruation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs584336 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs584336 come from?
GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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ICD10 N92: Excessive, frequent and irregular menstruation (rs584336). MyGeneLog™. https://www.mygenelog.com/variants/rs584336