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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 44,831 Chinese ancestry individuals; replicated in 22,648 Chinese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.195 higher (95% confidence interval 0.15-0.24); p = 1 × 10−17.
How common The T allele had a frequency of about 10% in the people studied.
What each result means
C/CNo copy of the version the research linked to Vitamin B12 in pregnancy. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Vitamin B12 in pregnancy. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Vitamin B12 in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs58403183 is a single position in the genome, in or near the CD320 gene. Published research associates it with vitamin b12 in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs58403183 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs58403183 come from?
GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Vitamin B12 in pregnancy (rs58403183). MyGeneLog™. https://www.mygenelog.com/variants/rs58403183