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Ratio of omega-6 fatty acids to omega-3 fatty acids

USP1 · rs583609

What the study found

Who was studied 115,006 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0428 lower (95% confidence interval 0.035-0.051); p = 7 × 10−25.

How common The T allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in the 3′ untranslated region of USP1.

What each result means

C/C No copy of the version the research linked to Ratio of omega-6 fatty acids to omega-3 fatty acids. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Ratio of omega-6 fatty acids to omega-3 fatty acids. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Ratio of omega-6 fatty acids to omega-3 fatty acids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs583609

What is rs583609?

rs583609 is a single position in the genome, in or near the USP1 gene. Published research associates it with ratio of omega-6 fatty acids to omega-3 fatty acids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs583609 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs583609 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ratio of omega-6 fatty acids to omega-3 fatty acids (rs583609). MyGeneLog™. https://www.mygenelog.com/variants/rs583609

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