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Cortical thickness

TUBA1B-AS1 · rs58336603

What the study found

Who was studied 35,657 White British ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−13.

How common The T allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 12, band 12q13.12 — in an intron of TUBA1B-AS1.

What each result means

C/C No copy of the version the research linked to Cortical thickness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cortical thickness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs58336603

What is rs58336603?

rs58336603 is a single position in the genome, in or near the TUBA1B-AS1 gene. Published research associates it with cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs58336603 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs58336603 come from?

GWAS Catalog, NeuroImage 2021, PMID:34560273. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical thickness (rs58336603). MyGeneLog™. https://www.mygenelog.com/variants/rs58336603

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