Standard
IgG fucosylation phenotypes (multivariate analysis)
IGH · rs58087925
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of IgG fucosylation phenotypes (multivariate analysis) — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgG fucosylation phenotypes (multivariate analysis).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgG fucosylation phenotypes (multivariate analysis) compared to the general population.
Source
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Shen X,
Klarić L,
Sharapov S,
Mangino M,
Ning Z,
Wu D,
Trbojević-Akmačić I,
Pučić-Baković M,
Rudan I,
Polašek O,
Hayward C,
Spector TD
and 3 more — show all
Nature communications · 2017 · PMID 28878392 · open access
Questions about rs58087925
What is rs58087925?
rs58087925 is a single position in the genome, in or near the IGH gene. Published research associates it with igg fucosylation phenotypes (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs58087925 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs58087925 come from?
GWAS Catalog, Nat Commun 2017, PMID:28878392. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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