A/APublished research associates this genotype with typical/baseline likelihood of Glomerular filtration rate — no copies of the reported risk allele.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glomerular filtration rate.
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glomerular filtration rate compared to the general population.
American journal of human genetics · 2016 · PMID 27588450 · open access
Questions about rs57989581
What is rs57989581?
rs57989581 is a single position in the genome, in or near the LRP2 gene. Published research associates it with glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs57989581 linked to?
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Does having rs57989581 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs57989581 come from?
GWAS Catalog, Am J Hum Genet 2016, PMID:27588450. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.