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Lateral thalamic nuclei volume

NDUFA5P5 · rs57977776

What the study found

Who was studied 30,114 white British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0875 lower (95% confidence interval 0.061-0.114); p = 9 × 10−11.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 3, band 3p11.1 — between genes, 9.4 kb from NDUFA5P5.

What each result means

C/C No copy of the version the research linked to Lateral thalamic nuclei volume. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lateral thalamic nuclei volume. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lateral thalamic nuclei volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs57977776

What is rs57977776?

rs57977776 is a single position in the genome, in or near the NDUFA5P5 gene. Published research associates it with lateral thalamic nuclei volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs57977776 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs57977776 come from?

GWAS Catalog, Nature communications 2021, PMID:34006833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lateral thalamic nuclei volume (rs57977776). MyGeneLog™. https://www.mygenelog.com/variants/rs57977776

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