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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 48,843 European ancestry cases, 1,190,837 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−10.
How common The T allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 10, band 10p11.23 — between genes, 2.2 kb from ZNF438.
What each result means
C/CNo copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35332129 · open access
Questions about rs57822625
What is rs57822625?
rs57822625 is a single position in the genome, in or near the near ZNF438 gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs57822625 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs57822625 come from?
GWAS Catalog, Nature communications 2022, PMID:35332129. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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