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Platelet distribution width in pregnancy

ZNF787 · rs578075

What the study found

Who was studied 94,541 Chinese ancestry individuals; replicated in 45,550 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0562 lower (95% confidence interval 0.04-0.072); p = 4 × 10−12.

How common The A allele had a frequency of about 62% in the people studied.

Where it sits Chromosome 19, band 19q13.43 — in an intron of ZNF787.

What each result means

A/A Two copies of the version the research linked to Platelet distribution width in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet distribution width in pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet distribution width in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs578075

What is rs578075?

rs578075 is a single position in the genome, in or near the ZNF787 gene. Published research associates it with platelet distribution width in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs578075 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs578075 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet distribution width in pregnancy (rs578075). MyGeneLog™. https://www.mygenelog.com/variants/rs578075

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